SPRC Suppresses Experimental Periodontitis by Modulating Th17/Treg Imbalance

SPRC Suppresses Experimental Periodontitis by Modulating Th17/Treg Imbalance

Object: The aims of the study were to explore the protective effects of S-propargyl-cysteine (SPRC) on periodontitis and to determine the underlying mechanisms.Methods: A rat periodontitis model was constructed by injecting LPS and SPRC (0, 25, and 50 mg/kg/d) was administered intraperitoneally. H2S...

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Bibliographic Details
Main Authors:	Qian Peng, Bingkun Zhao, Jie Lin, Haixia Liu, Rong Zhou, Dongmei Lan, Chao Yao, Shaohua Cong, Shen Tao, Yizhun Zhu, Raorao Wang, Shengcai Qi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-01-01
Series:	Frontiers in Bioengineering and Biotechnology
Subjects:	S-propargyl-cysteine periodontitis Th17 cells regulatory T cells ERK/CREB signalling pathway
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2021.737334/full

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