Involvement of orexin neurons in fasting- and central adenosine-induced hypothermia

Abstract We examined whether orexin neurons might play a protective role against fasting- and adenosine-induced hypothermia. We first measured body temperature (BT) in orexin neuron-ablated (ORX-AB) mice and wild-type (WT) controls during 24 hours of fasting. As expected, the magnitude of BT drop an...

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Bibliographic Details
Main Authors: Takahiro Futatsuki, Akira Yamashita, Khairunnisa Novita Ikbar, Akihiro Yamanaka, Kazunori Arita, Yasuyuki Kakihana, Tomoyuki Kuwaki
Format: Article
Language:English
Published: Nature Portfolio 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-21252-w