Phenotypic characterization of HIV-specific CD8+ T cells during early and chronic infant HIV-1 infection.

Phenotypic characterization of HIV-specific CD8+ T cells during early and chronic infant HIV-1 infection.

Although CD8(+) T cells play an important role in the containment of adult HIV-1 replication, their role in infant HIV-1 infection is not as well understood. Impaired HIV-specific CD8(+) T cell responses may underlie the persistently high viral loads observed in infants. We examined the frequency an...

Full description

Bibliographic Details
Main Authors: Jennifer A Slyker, Grace C John-Stewart, Tao Dong, Barbara Lohman-Payne, Marie Reilly, Ann Atzberger, Stephen Taylor, Elizabeth Maleche-Obimbo, Dorothy Mbori-Ngacha, Sarah L Rowland-Jones
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3105047?pdf=render

Internet

http://europepmc.org/articles/PMC3105047?pdf=render

Similar Items