Dendritic Cells and Myeloid Derived Suppressor Cells Fully Responsive to Stimulation via Toll-Like Receptor 4 Are Rapidly Induced from Bone-Marrow Cells by Granulocyte-Macrophage Colony-Stimulating Factor

Dendritic cells (DCs) are commonly generated from bone marrow (BM) progenitor cells with granulocyte-macrophage colony-stimulating factor (GM-CSF) alone or in combination with interleukin 4 (IL-4). These cells are often harvested post day 5, when they acquire maturation markers and can stimulate T c...

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Bibliographic Details
Main Authors: Ying Ying Kong, Kirsty Wilson, Vasso Apostolopoulos, Magdalena Plebanski
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/3/522