Molecular mechanisms of developmental pathways in neurological disorders: a pharmacological and therapeutic review

Molecular mechanisms of developmental pathways in neurological disorders: a pharmacological and therapeutic review

Developmental signalling pathways such as Wnt/β-catenin, Notch and Sonic hedgehog play a central role in nearly all the stages of neuronal development. The term ‘embryonic’ might appear to be a misnomer to several people because these pathways are functional during the early stages of embryonic deve...

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Main Authors: Niraj Kumar Jha, Wei-Chih Chen, Sanjay Kumar, Rajni Dubey, Lung-Wen Tsai, Rohan Kar, Saurabh Kumar Jha, Piyush Kumar Gupta, Ankur Sharma, Rohit Gundamaraju, Kumud Pant, Shalini Mani, Sandeep Kumar Singh, Ricardo B. Maccioni, Tirtharaj Datta, Sachin Kumar Singh, Gaurav Gupta, Parteek Prasher, Kamal Dua, Abhijit Dey, Charu Sharma, Yasir Hayat Mughal, Janne Ruokolainen, Kavindra Kumar Kesari, Shreesh Ojha
Format: Article
Language:English
Published: The Royal Society 2022-03-01
Series:Open Biology
Subjects:
Wnt/β-catenin
Notch
Sonic hedgehog
CNS
neurodegeneration
neurotherapeutics
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.210289

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https://royalsocietypublishing.org/doi/10.1098/rsob.210289

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