Deciphering comprehensive features of tumor microenvironment controlled by chromatin regulators to predict prognosis and guide therapies in uterine corpus endometrial carcinoma

Deciphering comprehensive features of tumor microenvironment controlled by chromatin regulators to predict prognosis and guide therapies in uterine corpus endometrial carcinoma

BackgroundDysregulation of chromatin regulators (CRs) can perturb the tumor immune microenvironment, but the underlying mechanism remains unclear. We focused on uterine corpus endometrial carcinoma (UCEC) and used gene expression data from TCGA-UCEC to investigate this mechanism.MethodsWe used weigh...

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Bibliographic Details
Main Authors: Qihui Wu, Ruotong Tian, Jiaxin Liu, Chunlin Ou, Yimin Li, Xiaodan Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
chromatin regulator
tumor immune microenvironment
DNA methylation
prognostic model
immunotherapy
uterine corpus endometrial carcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1139126/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1139126/full

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