Disruption of prostate epithelial differentiation pathways and prostate cancer development

A major problem in the prostate cancer field is the inability to distinguish aggressive from indolent disease. This gap in knowledge stems from the fact that the mechanisms which trigger tumorigenesis in the prostate are poorly understood. While specific known genetic alterations are very common in...

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Bibliographic Details
Main Authors: Sander B Frank, Cindy K Miranti
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00273/full