Improving retinal mitochondrial function as a treatment for age-related macular degeneration

Improving retinal mitochondrial function as a treatment for age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness among the elderly. Currently, there are no treatments for dry AMD, which is characterized by the death of retinal pigment epithelium (RPE) and photoreceptors. Reports from human donors with AMD suggest that RPE mitochondrial de...

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Bibliographic Details
Main Authors: Mara C. Ebeling, Jorge R. Polanco, Jun Qu, Chengjian Tu, Sandra R. Montezuma, Deborah A. Ferrington
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Redox Biology
Subjects:
Age-related macular degeneration
Retinal pigment epithelium
Mitochondrial function
Rapamycin
Pyrroloquinoline quinone
Nicotinamide mononucleotide
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172030094X

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http://www.sciencedirect.com/science/article/pii/S221323172030094X

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