Comparison of different technologies for producing recombinant adeno-associated virus on a laboratory scale

Comparison of different technologies for producing recombinant adeno-associated virus on a laboratory scale

Adeno-associated virus vectors are among the most promising ones for the delivery of transgenes to various organs and tissues. Recombinant adeno-associated virus (rAAV) is able to transduce both dividing and non-dividing cells, has low immunogenicity, and is able to provide long-term expression of t...

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Bibliographic Details
Main Authors: E. I. Ryabova, A. A. Derkaev, I. B. Esmagambetov, D. V. Shcheblyakov, M. A. Dovgiy, D. V. Byrikhina, V. V. Prokofiev, I. P. Chemodanova
Format: Article
Language:Russian
Published: Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2021-12-01
Series:Биопрепараты: Профилактика, диагностика, лечение
Subjects:
adeno-associated viral vector
single domain antibodies
transfection
affinity chromatography
hek293 cell culture
bioreactor
supercoiled form of plasmid dna
Online Access:https://www.biopreparations.ru/jour/article/view/354

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https://www.biopreparations.ru/jour/article/view/354

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