Target Recognition– and HCR Amplification–Induced In Situ Electrochemical Signal Probe Synthesis Strategy for Trace ctDNA Analysis

Target Recognition– and HCR Amplification–Induced In Situ Electrochemical Signal Probe Synthesis Strategy for Trace ctDNA Analysis

An electrochemical-DNA (E-DNA) sensor was constructed by using DNA metallization to produce an electrochemical signal reporter in situ and hybridization chain reaction (HCR) as signal amplification strategy. The cyclic voltammetry (CV) technique was used to characterize the electrochemical solid-sta...

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Bibliographic Details
Main Authors: Aiting Cai, Luxia Yang, Xiaoxia Kang, Jinxia Liu, Feng Wang, Haiwei Ji, Qi Wang, Mingmin Wu, Guo Li, Xiaobo Zhou, Yuling Qin, Li Wu
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biosensors
Subjects:
DNA metallization
ctDNA
HCR
Exo Ι
E-DNA sensor
Online Access:https://www.mdpi.com/2079-6374/12/11/989

Internet

https://www.mdpi.com/2079-6374/12/11/989

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