Compartmentalised cAMP signalling in the primary cilium

cAMP is a universal second messenger that relies on precise spatio-temporal regulation to control varied, and often opposing, cellular functions. This is achieved via selective activation of effectors embedded in multiprotein complexes, or signalosomes, that reside at distinct subcellular locations....

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Bibliographic Details
Main Authors: Ester Paolocci, Manuela Zaccolo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1187134/full