Clonal Hematopoiesis: A New Step Linking Inflammation to Heart Failure

Heart failure is a common disease with poor prognosis that is associated with cardiac immune cell infiltration and dysregulated cytokine expression. Recently, the clonal expansion of hematopoietic cells with acquired (i.e., nonheritable) DNA mutations, a process referred to as clonal hematopoiesis,...

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Bibliographic Details
Main Authors: Yoshimitsu Yura, MD, PhD, Soichi Sano, MD, PhD, Kenneth Walsh, PhD
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:JACC: Basic to Translational Science
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X19302591