A wild rice-derived peptide R14 ameliorates monosodium urate crystals-induced IL-1β secretion through inhibition of NF-κB signaling and NLRP3 inflammasome activation

A wild rice-derived peptide R14 ameliorates monosodium urate crystals-induced IL-1β secretion through inhibition of NF-κB signaling and NLRP3 inflammasome activation

Gout is an inflammatory arthritis initiated by the deposition of monosodium urate crystals (MSU) around the joints and surrounding tissues. MSU crystals activate the nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) inflammasome to the release of interleukin-1...

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Bibliographic Details
Main Authors: Supattra Charoenwutthikun, Kasem Chanjitwiriya, Sittiruk Roytrakul, Duangkamol Kunthalert
Format: Article
Language:English
Published: PeerJ Inc. 2023-05-01
Series:PeerJ
Subjects:
Gout
Monosodium urate
Interleukin-1β
NF-κB
Inflammasome
Online Access:https://peerj.com/articles/15295.pdf

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https://peerj.com/articles/15295.pdf

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