Absolute Winding Number Differentiates Mouse Spatial Navigation Strategies With Genetic Risk for Alzheimer’s Disease

Absolute Winding Number Differentiates Mouse Spatial Navigation Strategies With Genetic Risk for Alzheimer’s Disease

Spatial navigation and orientation are emerging as promising markers for altered cognition in prodromal Alzheimer’s disease, and even in cognitively normal individuals at risk for Alzheimer’s disease. The different APOE gene alleles confer various degrees of risk. The APOE2 allele is considered prot...

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Bibliographic Details
Main Authors: Alexandra Badea, Didong Li, Andrei R. Niculescu, Robert J. Anderson, Jacques A. Stout, Christina L. Williams, Carol A. Colton, Nobuyo Maeda, David B. Dunson
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Neuroscience
Subjects:
APOE
Alzheimer’s disease
brain
mouse
connectivity
memory
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.848654/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.848654/full

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