Targeted metabolic profiling of urinary steroids with a focus on analytical accuracy and sample stability

Targeted metabolic profiling of urinary steroids with a focus on analytical accuracy and sample stability

Introduction: Preoperative diagnostic workup of adrenal tumors is based on imaging and hormone analyses, but charged with uncertainties. Steroid profiling by liquid chromatography tandem mass spectrometry (LC-MS/MS) in 24-h urine has shown potential to discriminate benign and malignant adrenal tumor...

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Bibliographic Details
Main Authors: Nora Vogg, Tobias Müller, Andreas Floren, Thomas Dandekar, Oliver Scherf-Clavel, Martin Fassnacht, Matthias Kroiss, Max Kurlbaum
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Journal of Mass Spectrometry and Advances in the Clinical Lab
Subjects:
Adrenal tumors
Adrenocortical carcinoma
Steroid profiling
Urinary steroids
Mass spectrometry
LC–MS/MS
Online Access:http://www.sciencedirect.com/science/article/pii/S2667145X22000244

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http://www.sciencedirect.com/science/article/pii/S2667145X22000244

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