Rosa laevigata Attenuates Allergic Asthma Exacerbated by Water-Soluble PM by Downregulating the MAPK Pathway

Rosa laevigata Attenuates Allergic Asthma Exacerbated by Water-Soluble PM by Downregulating the MAPK Pathway

Exposure to water-soluble particulate matter (WPM) containing heavy metals can cause severe inflammatory responses and trigger and exacerbate the onset of asthma. As a follow-up study of Rosa laevigata (RL), this study analyzed the therapeutic effects and mechanisms of oral and intratracheal adminis...

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Bibliographic Details
Main Authors: Hyun Min Ko, Seung-Han Choi, Wona Jee, Seung-Hyeon Lee, Doil Park, Ji Hoon Jung, Beom-Joon Lee, Kwan-Il Kim, Hee-Jae Jung, Hyeung-Jin Jang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
Rosa laevigata
particulate matter
asthma
inflammation
IgE
cytokines
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.925502/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.925502/full

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