ARHGEF18 is a flow-responsive exchange factor controlling endothelial tight junctions and vascular leakage
Summary: The shear stress resulting from blood flow is a major regulator of endothelial cell (EC) biology and morphology. Rho protein-mediated cytoskeleton remodeling is an early and essential step of EC responses to flow. However, how Rho protein signaling is controlled by shear stress remains uncl...
Autori principali: | , , , , , , , , , |
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Natura: | Articolo |
Lingua: | English |
Pubblicazione: |
Elsevier
2025-03-01
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Serie: | Cell Reports |
Soggetti: | |
Accesso online: | http://www.sciencedirect.com/science/article/pii/S2211124725000592 |