Novel plasma exosome biomarkers for prostate cancer progression in co-morbid metabolic disease

Novel plasma exosome biomarkers for prostate cancer progression in co-morbid metabolic disease

Comorbid Type 2 diabetes (T2D), a metabolic complication of obesity, associates with worse cancer outcomes for prostate, breast, head and neck, colorectal and several other solid tumors. However, the molecular mechanisms remain poorly understood. Emerging evidence shows that exosomes carry miRNAs in...

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Bibliographic Details
Main Authors: Naser Jafari, Andrew Chen, Manohar Kolla, Isabella R. Pompa, Yuhan Qiu, Rebecca Yu, Pablo Llevenes, Christina S. Ennis, Joakin Mori, Kiana Mahdaviani, Meredith Halpin, Gretchen A. Gignac, Christopher M. Heaphy, Stefano Monti, Gerald V. Denis
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Advances in Cancer Biology - Metastasis
Subjects:
Epithelial-mesenchymal transition
Epithelial plasticity
Prostate cancer
Castration-resistant
Epigenetic regulators
BET proteins
Online Access:http://www.sciencedirect.com/science/article/pii/S2667394022000478

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http://www.sciencedirect.com/science/article/pii/S2667394022000478

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