The Expression of Hippocampal NRG1/ErbB4 Correlates With Neuronal Apoptosis, but Not With Glial Activation During Chronic Cerebral Hypoperfusion

The Expression of Hippocampal NRG1/ErbB4 Correlates With Neuronal Apoptosis, but Not With Glial Activation During Chronic Cerebral Hypoperfusion

Permanent bilateral common carotid occlusion (2VO) is well-established to investigate the chronic cerebral hypoperfusion (CCH)-induced cognitive deficits. Besides, previous studies suggested that disturbance of Neuregulin1 (NRG1)/ErbB4 signaling is associated with cognitive impairments, as well as n...

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Bibliographic Details
Main Authors: Yue Hei, Rong Chen, Xicai Yi, Lizhou Wei, Qianfa Long, Weiping Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
chronic cerebral hypoperfusion
neuronal apoptosis
glial activation
NRG1
ErbB4
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00149/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2018.00149/full

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