Phage-Derived Protein Induces Increased Platelet Activation and Is Associated with Mortality in Patients with Invasive Pneumococcal Disease

ABSTRACT To improve our understanding about the severity of invasive pneumococcal disease (IPD), we investigated the association between the genotype of Streptococcus pneumoniae and disease outcomes for 349 bacteremic patients. A pneumococcal genome-wide association study (GWAS) demonstrated a stron...

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Bibliographic Details
Main Authors: Rahajeng N. Tunjungputri, Fredrick M. Mobegi, Amelieke J. Cremers, Christa E. van der Gaast-de Jongh, Gerben Ferwerda, Jacques F. Meis, Nel Roeleveld, Stephen D. Bentley, Alexander S. Pastura, Sacha A. F. T. van Hijum, Andre J. van der Ven, Quirijn de Mast, Aldert Zomer, Marien I. de Jonge
Format: Article
Language:English
Published: American Society for Microbiology 2017-03-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01984-16