Cassette deletion in multiple shRNA lentiviral vectors for HIV-1 and its impact on treatment success
<p>Abstract</p> <p>Background</p> <p>Multiple short hairpin RNA (shRNA) gene therapy strategies are currently being investigated for treating viral diseases such as HIV-1. It is important to use several different shRNAs to prevent the emergence of treatment-resistant st...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-10-01
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Series: | Virology Journal |
Online Access: | http://www.virologyj.com/content/6/1/184 |