Cassette deletion in multiple shRNA lentiviral vectors for HIV-1 and its impact on treatment success

Cassette deletion in multiple shRNA lentiviral vectors for HIV-1 and its impact on treatment success

<p>Abstract</p> <p>Background</p> <p>Multiple short hairpin RNA (shRNA) gene therapy strategies are currently being investigated for treating viral diseases such as HIV-1. It is important to use several different shRNAs to prevent the emergence of treatment-resistant st...

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Bibliographic Details
Main Authors: Shen Sylvie W, Elliott Fiona A, Boyd Maureen P, Millington Michelle L, Arndt Allison J, Jaramillo Angel B, Tran Anna, Yu Yi-Hsin, Mcintyre Glen J, Murray John M, Applegate Tanya L
Format: Article
Language:English
Published: BMC 2009-10-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/6/1/184

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