Altered PLCβ/IP<sub>3</sub>/Ca<sup>2+</sup> Signaling Pathway Activated by GPRCs in Olfactory Neuronal Precursor Cells Derived from Patients Diagnosed with Schizophrenia

Altered PLCβ/IP<sub>3</sub>/Ca<sup>2+</sup> Signaling Pathway Activated by GPRCs in Olfactory Neuronal Precursor Cells Derived from Patients Diagnosed with Schizophrenia

<b>Background</b>: Schizophrenia (SZ) is a multifactorial chronic psychiatric disorder with a worldwide prevalence of 1%. Altered expression of PLCβ occurs in SZ patients, suggesting alterations in the PLCβ/IP<sub>3</sub>/Ca<sup>2+</sup> signaling pathway. This ca...

Full description

Bibliographic Details
Main Authors: Zuly A. Sánchez-Florentino, Bianca S. Romero-Martínez, Edgar Flores-Soto, Luis M. Montaño, Bettina Sommer, Marcela Valdés-Tovar, Jesús Argueta, Eduardo Calixto, Arnoldo Aquino-Gálvez, Manuel Castillejos-López, Héctor Serrano, Juan C. Gomez-Verjan, Germán O. López-Riquelme, Gloria A. Benítez-King, Ruth Jaimez, Héctor Solís-Chagoyán
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Biomedicines
Subjects:
human olfactory neuronal stem cells
calcium signaling
PLCβ
IP<sub>3</sub>
schizophrenia
Online Access:https://www.mdpi.com/2227-9059/12/10/2343

Internet

https://www.mdpi.com/2227-9059/12/10/2343

Similar Items