Pharmacological and toxicological studies of a novel goserelin acetate extended-release microspheres in rats

LY01005 is an investigational new drug product of goserelin acetate which is formulated as extended-release microspheres for intramuscular injection. To support the proposed clinical trials and marketing application of LY01005, pharmacodynamics, pharmacokinetics and toxicity studies were performed i...

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Bibliographic Details
Main Authors: Mao Yutong, Ye Liang, Sha Chunjie, Guan Xiaolin, Gong Xiaoyan, Dong Lin, Du Guangying, Zhang Xuemei, Cen Xiaobo, Tian Jingwei, Yu Pengfei, Wang Hongbo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1125255/full