TRPV3 Channels Mediate Strontium-Induced Mouse-Egg Activation

In mammals, calcium influx is required for oocyte maturation and egg activation. The molecular identities of the calcium-permeant channels that underlie the initiation of embryonic development are not established. Here, we describe a transient receptor potential (TRP) ion channel current activated b...

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Bibliographic Details
Main Authors: Ingrid Carvacho, Hoi Chang Lee, Rafael A. Fissore, David E. Clapham
Format: Article
Language:English
Published: Elsevier 2013-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713006566