Gsk-3$ \beta $ aggravates depression symptoms in a chronic stress mouse model

Depression caused by genetic and environmental factors is acomplicated disease. Here, it is demonstrated that glycogen synthase kinase-3$\beta$ is highly expressed and phosphorylated in the brain of a chronic stress mouse. Inhibition of glycogen synthase kinase-3$\beta$ leads to decreased depression...

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Bibliographic Details
Main Author: Hong Peng, Hong-bin Wang, Ling Wang, Bing Zhou, Xiao-yong Li, Jian Tan
Format: Article
Language:English
Published: IMR Press 2018-05-01
Series:Journal of Integrative Neuroscience
Subjects:
Online Access:https://jin.imrpress.com/fileup/1757-448X/PDF/1546080058721-1436308511.pdf