Generation of Powerful Human Tolerogenic Dendritic Cells by Lentiviral-Mediated IL-10 Gene Transfer

Generation of Powerful Human Tolerogenic Dendritic Cells by Lentiviral-Mediated IL-10 Gene Transfer

The prominent role of dendritic cells (DC) in promoting tolerance and the development of methods to generate clinical grade products allowed the clinical application of tolerogenic DC (tolDC)-based therapies for controlling unwanted immune responses. We established an efficient method to generate to...

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Bibliographic Details
Main Authors: Michela Comi, Giada Amodio, Laura Passeri, Marta Fortunato, Francesca Romana Santoni de Sio, Grazia Andolfi, Anna Kajaste-Rudnitski, Fabio Russo, Luca Cesana, Silvia Gregori
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
IL-10
cell therapy
immune tolerance
allogeneic transplantation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01260/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01260/full

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