Selective Inhibition of IL-6 Trans-Signaling Has No Beneficial Effect on the Posttraumatic Cytokine Release after Multiple Trauma in Mice

Selective Inhibition of IL-6 Trans-Signaling Has No Beneficial Effect on the Posttraumatic Cytokine Release after Multiple Trauma in Mice

While improvements in pre-hospital and in-hospital care allow more multiple trauma patients to advance to intensive care, the incidence of posttraumatic multiple organ dysfunction syndrome (MODS) is on the rise. Herein, the influence of a selective IL-6 trans-signaling inhibition on posttraumatic cy...

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Bibliographic Details
Main Authors: Jil-Madeline Homeier, Katrin Bundkirchen, Marcel Winkelmann, Tilman Graulich, Borna Relja, Claudia Neunaber, Christian Macke
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Life
Subjects:
multiple trauma
MODS
sgp130Fc
trans-signaling
inflammatory cytokines
Online Access:https://www.mdpi.com/2075-1729/11/11/1252

Internet

https://www.mdpi.com/2075-1729/11/11/1252

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