Effector memory Th1 CD4 T cells are maintained in a mouse model of chronic malaria.

Protection against malaria often decays in the absence of infection, suggesting that protective immunological memory depends on stimulation. Here we have used CD4(+) T cells from a transgenic mouse carrying a T cell receptor specific for a malaria protein, Merozoite Surface Protein-1, to investigate...

Full description

Bibliographic Details
Main Authors: Robin Stephens, Jean Langhorne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2991260?pdf=render