Ovulation sources coagulation protease cascade and hepatocyte growth factor to support physiological growth and malignant transformation

The fallopian tube fimbrial epithelium, which is exposed to the follicular fluid (FF) contents of ovulation, is regarded as the main origin of ovarian high-grade serous carcinoma. Previously, we found that growth factors in FF, such as IGF2, are responsible for the malignant transformation of fallop...

Full description

Bibliographic Details
Main Authors: Hsuan-Shun Huang, Pao-Chu Chen, Sung-Chao Chu, Ming-Hsun Lee, Chi-Ya Huang, Tang-Yuan Chu
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558621000816