MgO NPs catalyzed the synthesis of novel pyridin-3-yl-pyrimidin-2-yl-aminophenyl-amide derivatives and evaluation of pharmacokinetic profiles and biological activity

In this study, novel pyridin-3-yl-pyrimidin-2-yl-aminophenyl-amide derivatives using two methods, namely, using trimethylamine as a classical method and using magnesium oxide nanoparticles, were synthesized. Biological activities of the derivatives such as inhibitors of receptor tyrosine kinase, pha...

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Bibliographic Details
Main Authors: Ibtihal Haitham Gani, Zaid Al-Obaidi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Materials
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmats.2023.1057677/full