Cholinergic modulation of the CAN current may adjust neural dynamics for active memory maintenance, spatial navigation and time-compressed replay

Cholinergic modulation of the CAN current may adjust neural dynamics for active memory maintenance, spatial navigation and time-compressed replay

Suppression of cholinergic receptors and inactivation of the septum impair short-term memory, and disrupt place cell and grid cell activity in the medial temporal lobe (MTL). Location-dependent hippocampal place cell firing during active waking, when the acetylcholine level is high, switches to time...

Full description

Bibliographic Details
Main Authors: Motoharu eYoshida, Beate eKnauer, Arthur eJochems
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-03-01
Series:Frontiers in Neural Circuits
Subjects:
Acetylcholine
Hippocampus
spatial navigation
short-term memory
encoding
consolidation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2012.00010/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncir.2012.00010/full

Similar Items