Plasma N-Acetylaspartate Is Related to Age, Obesity, and Glucose Metabolism: Effects of Antidiabetic Treatment and Bariatric Surgery

Plasma N-Acetylaspartate Is Related to Age, Obesity, and Glucose Metabolism: Effects of Antidiabetic Treatment and Bariatric Surgery

Background: N-acetylaspartate (NAA) is synthesized only by neurons and is involved in neuronal metabolism and axonal myelination. NAA is the strongest signal on brain magnetic resonance spectroscopy, and its concentration have been associated with cognitive dysfunction in neurodegenerative diseases,...

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Bibliographic Details
Main Authors: Giuseppe Daniele, Beatrice Campi, Alessandro Saba, Simone Codini, Annamaria Ciccarone, Laura Giusti, Stefano Del Prato, Russel L. Esterline, Ele Ferrannini
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Endocrinology
Subjects:
N-acetylaspartate
neuronal function
type 2 diabetes
obesity
dapagliflozin
exenatide
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00216/full

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https://www.frontiersin.org/article/10.3389/fendo.2020.00216/full

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