Cerebral small vessel disease: Pathological mechanisms and potential therapeutic targets

Cerebral small vessel disease: Pathological mechanisms and potential therapeutic targets

Cerebral small vessel disease (CSVD) represents a diverse cluster of cerebrovascular diseases primarily affecting small arteries, capillaries, arterioles and venules. The diagnosis of CSVD relies on the identification of small subcortical infarcts, lacunes, white matter hyperintensities, perivascula...

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Bibliographic Details
Main Authors: Yue Gao, Di Li, Jianwen Lin, Aline M. Thomas, Jianyu Miao, Dong Chen, Shen Li, Chengyan Chu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Aging Neuroscience
Subjects:
cerebral small vessel disease
cognitive impairment
endothelial dysfunction
blood-brain barrier breakdown
white matter change
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.961661/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2022.961661/full

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