Repurposing Disulfiram as an Antifungal Agent: Development of a New Disulfiram Vaginal Mucoadhesive Gel

Repurposing Disulfiram as an Antifungal Agent: Development of a New Disulfiram Vaginal Mucoadhesive Gel

Alternative formulations need to be developed to improve the efficacy of treatments administered via the vaginal route. Mucoadhesive gels with disulfiram, a molecule that was originally approved as an antialcoholism drug, offer an attractive alternative to treat vaginal candidiasis. The aim of the c...

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Bibliographic Details
Main Authors: Maria Lajarin-Reinares, Iria Naveira-Souto, Mireia Mallandrich, Joaquim Suñer-Carbó, Montserrat Llagostera Casas, Maria Angels Calvo, Francisco Fernandez-Campos
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Pharmaceutics
Subjects:
disulfiram
<i>Candida</i> spp.
mucoadhesion
ATP-binding cassette
resistant
vaginitis
Online Access:https://www.mdpi.com/1999-4923/15/5/1436

Internet

https://www.mdpi.com/1999-4923/15/5/1436

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