The monoterpene 1,8-cineole prevents cerebral edema in a murine model of severe malaria.

1,8-Cineole is a naturally occurring compound found in essential oils of different plants and has well-known anti-inflammatory and antimicrobial activities. In the present work, we aimed to investigate its potential antimalarial effect, using the following experimental models: (1) the erythrocytic c...

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Main Authors: Edgleyson C Dos Santos, Leandro S Silva, Alessandro S Pinheiro, Douglas E Teixeira, Diogo B Peruchetti, Rodrigo P Silva-Aguiar, Camila H C Wendt, Kildare R Miranda, Andrelina N Coelho-de-Souza, José Henrique Leal-Cardoso, Celso Caruso-Neves, Ana Acacia S Pinheiro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0268347