Emerging role of sirtuins on tumorigenesis: possible link between aging and cancer

Aging is the strongest risk factor for cancer development,suggesting that molecular crosstalks between aging andtumorigenesis exist in many cellular pathways. Recently,Sirtuins (Sirt1-7), the mammalian homologues of aging-relatedsir2α in yeast, have been shown to modulate several majorcellular pathw...

Full description

Bibliographic Details
Main Authors: Yong I. Cha, Hyun-Seok Kim
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2013-09-01
Series:BMB Reports
Subjects:
Online Access:http://bmbreports.org/jbmb/pdf.php?data=MTMxMDA3MTZAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0Ni05JTVEMTMwOTI2MTcxN18lMjg0MjktNDM4JTI5Qk1CXzEzLTE4MC5wZGY=