SH2B3 (LNK) rs3184504 polymorphism is correlated with JAK2 V617F-positive myeloproliferative neoplasms

SH2B3 (LNK) rs3184504 polymorphism is correlated with JAK2 V617F-positive myeloproliferative neoplasms

Background: Pathogenesis and phenotypic diversity in myeloproliferative neoplasms (MPN) cannot be fully explained by the currently known acquired mutations alone. Some susceptible germline variants of different genes have been proved to be associated with the development of these diseases. The goal...

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Bibliographic Details
Main Authors: Trifa Adrian P., Lighezan Diana L., Jucan Cristina, Tripon Florin, Arbore Dana R., Bojan Anca, Gligor-Popa Ștefana, Pop Raluca M., Dima Delia, Bănescu Claudia
Format: Article
Language:English
Published: Sciendo 2020-07-01
Series:Romanian Journal of Laboratory Medicine
Subjects:
myeloproliferative neoplasms
somatic mutations
genetic predisposition
Online Access:https://doi.org/10.2478/rrlm-2020-0025

Internet

https://doi.org/10.2478/rrlm-2020-0025

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