Use of external evidence for design and Bayesian analysis of clinical trials: a qualitative study of trialists’ views

Abstract Background Evidence from previous studies is often used relatively informally in the design of clinical trials: for example, a systematic review to indicate whether a gap in the current evidence base justifies a new trial. External evidence can be used more formally in both trial design and...

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Bibliographic Details
Main Authors: Gemma L. Clayton, Daisy Elliott, Julian P. T. Higgins, Hayley E. Jones
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-021-05759-8