A pH-responsive bi-MIL-88B MOF coated with folic acid-conjugated chitosan as a promising nanocarrier for targeted drug delivery of 5-Fluorouracil

A pH-responsive bi-MIL-88B MOF coated with folic acid-conjugated chitosan as a promising nanocarrier for targeted drug delivery of 5-Fluorouracil

Cancer has remained one of the leading causes of death worldwide, with a lack of effective treatment. The intrinsic shortcomings of conventional therapeutics regarding tumor specificity and non-specific toxicity prompt us to look for alternative therapeutics to mitigate these limitations. In this re...

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Bibliographic Details
Main Authors: Muhammad Usman Akbar, Saadullah Khattak, Malik Ihsanullah Khan, Umair Ali Khan Saddozai, Nemat Ali, Abdullah F. AlAsmari, Muhammad Zaheer, Muhammad Badar
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Pharmacology
Subjects:
metal-organic framework
folic acid -chitosan
stimuli responsive
drug delivery
targeted therapy
anticancer
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1265440/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1265440/full

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