ChAd155-RSV vaccine is immunogenic and efficacious against bovine RSV infection-induced disease in young calves

A pediatric RSV vaccine is an unmet medical need, even after >50 years of effort. Here, the authors show that a chimpanzee adenovirus based RSV vaccine candidate protects calves from disease upon RSV infection, regardless of the time after vaccination (1 or 4 months) or the presence of maternal a...

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Bibliographic Details
Main Authors: Rineke de Jong, Norbert Stockhofe-Zurwieden, Judith Bonsing, Kai-Fen Wang, Sarah Vandepaer, Badiaa Bouzya, Jean-François Toussaint, Ilse Dieussaert, Haifeng Song, Ann-Muriel Steff
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33649-3