ChAd155-RSV vaccine is immunogenic and efficacious against bovine RSV infection-induced disease in young calves
A pediatric RSV vaccine is an unmet medical need, even after >50 years of effort. Here, the authors show that a chimpanzee adenovirus based RSV vaccine candidate protects calves from disease upon RSV infection, regardless of the time after vaccination (1 or 4 months) or the presence of maternal a...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-33649-3 |
| _version_ | 1798028546776498176 |
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| author | Rineke de Jong Norbert Stockhofe-Zurwieden Judith Bonsing Kai-Fen Wang Sarah Vandepaer Badiaa Bouzya Jean-François Toussaint Ilse Dieussaert Haifeng Song Ann-Muriel Steff |
| author_facet | Rineke de Jong Norbert Stockhofe-Zurwieden Judith Bonsing Kai-Fen Wang Sarah Vandepaer Badiaa Bouzya Jean-François Toussaint Ilse Dieussaert Haifeng Song Ann-Muriel Steff |
| author_sort | Rineke de Jong |
| collection | DOAJ |
| description | A pediatric RSV vaccine is an unmet medical need, even after >50 years of effort. Here, the authors show that a chimpanzee adenovirus based RSV vaccine candidate protects calves from disease upon RSV infection, regardless of the time after vaccination (1 or 4 months) or the presence of maternal antibodies. |
| first_indexed | 2024-04-11T19:10:05Z |
| format | Article |
| id | doaj.art-a59e99feeb0c41a997df7bed33028bd5 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-11T19:10:05Z |
| publishDate | 2022-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-a59e99feeb0c41a997df7bed33028bd52022-12-22T04:07:39ZengNature PortfolioNature Communications2041-17232022-10-0113111410.1038/s41467-022-33649-3ChAd155-RSV vaccine is immunogenic and efficacious against bovine RSV infection-induced disease in young calvesRineke de Jong0Norbert Stockhofe-Zurwieden1Judith Bonsing2Kai-Fen Wang3Sarah Vandepaer4Badiaa Bouzya5Jean-François Toussaint6Ilse Dieussaert7Haifeng Song8Ann-Muriel Steff9Wageningen Bioveterinary Research, Wageningen University & ResearchWageningen Bioveterinary Research, Wageningen University & ResearchWageningen Bioveterinary Research, Wageningen University & ResearchGSKCONSULTYS Benelux S.AGSK, Rue de l’Institut 89GSK, Rue de l’Institut 89GSK, Rue de l’Institut 89GSKGSKA pediatric RSV vaccine is an unmet medical need, even after >50 years of effort. Here, the authors show that a chimpanzee adenovirus based RSV vaccine candidate protects calves from disease upon RSV infection, regardless of the time after vaccination (1 or 4 months) or the presence of maternal antibodies.https://doi.org/10.1038/s41467-022-33649-3 |
| spellingShingle | Rineke de Jong Norbert Stockhofe-Zurwieden Judith Bonsing Kai-Fen Wang Sarah Vandepaer Badiaa Bouzya Jean-François Toussaint Ilse Dieussaert Haifeng Song Ann-Muriel Steff ChAd155-RSV vaccine is immunogenic and efficacious against bovine RSV infection-induced disease in young calves Nature Communications |
| title | ChAd155-RSV vaccine is immunogenic and efficacious against bovine RSV infection-induced disease in young calves |
| title_full | ChAd155-RSV vaccine is immunogenic and efficacious against bovine RSV infection-induced disease in young calves |
| title_fullStr | ChAd155-RSV vaccine is immunogenic and efficacious against bovine RSV infection-induced disease in young calves |
| title_full_unstemmed | ChAd155-RSV vaccine is immunogenic and efficacious against bovine RSV infection-induced disease in young calves |
| title_short | ChAd155-RSV vaccine is immunogenic and efficacious against bovine RSV infection-induced disease in young calves |
| title_sort | chad155 rsv vaccine is immunogenic and efficacious against bovine rsv infection induced disease in young calves |
| url | https://doi.org/10.1038/s41467-022-33649-3 |
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