Epigenetic biomarker screening by FLIM-FRET for combination therapy in ER+ breast cancer

Abstract Hormone-dependent gene expression involves dynamic and orchestrated regulation of epigenome leading to a cancerous state. Estrogen receptor (ER)-positive breast cancer rely on chromatin remodeling and association with epigenetic factors in inducing ER-dependent oncogenesis and thus cell ove...

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Detalhes bibliográficos
Main Authors: Wenjie Liu, Yi Cui, Wen Ren, Joseph Irudayaraj
Formato: Artigo
Idioma:English
Publicado em: BMC 2019-01-01
Colecção:Clinical Epigenetics
Assuntos:
Acesso em linha:http://link.springer.com/article/10.1186/s13148-019-0620-6