3-Hydroxypropane-1,2-Diyl Dipalmitoleate—A Natural Compound with Dual Roles (CB1 Agonist/FAAH1 Blocker) in Inhibiting Ovarian Cancer Cell Line

3-Hydroxypropane-1,2-Diyl Dipalmitoleate—A Natural Compound with Dual Roles (CB1 Agonist/FAAH1 Blocker) in Inhibiting Ovarian Cancer Cell Line

Though it was once known that upregulated Cannabinoid Receptor (CB1) and downregulated Fatty Acid Amide Hydrolase (FAAH1) are associated with tumour aggressiveness and metastasis, it is now clear that upregulated CB1 levels more than a certain point cause accumulation of ceramide and directs cells t...

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Bibliographic Details
Main Authors: Christina Vijayaraghavan Sathynathan, Lakshmi Sundaram Raman, Sivamurugan Vajiravelu, Thirumal D. Kumar, Thyagarajan Sadras Panchatcharam, Gopinathan Narasimhan, George C. Priya Doss, Mary Elizabeth Gnanambal Krishnan
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Pharmaceuticals
Subjects:
Cannabinoid Receptor 1 (CB1)
Fatty Acid Amide Hydrolase 1 (FAAH1)
ovarian cancer
<i>Conus inscriptus</i>
3-hydroxypropane-1,2-diyl dipalmitoleate
molecular modelling
Online Access:https://www.mdpi.com/1424-8247/14/3/255

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https://www.mdpi.com/1424-8247/14/3/255

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