SERPINE2 promotes liver cancer metastasis by inhibiting c‐Cbl‐mediated EGFR ubiquitination and degradation

SERPINE2 promotes liver cancer metastasis by inhibiting c‐Cbl‐mediated EGFR ubiquitination and degradation

Abstract Background Liver cancer is a malignancy with high morbidity and mortality rates. Serpin family E member 2 (SERPINE2) has been reported to play a key role in the metastasis of many tumors. In this study, we aimed to investigate the potential mechanism of SERPINE2 in liver cancer metastasis....

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Bibliographic Details
Main Authors: Shiyu Zhang, Xing Jia, Haojiang Dai, Xingxin Zhu, Wenfeng Song, Suchen Bian, Hao Wu, Shinuo Chen, Yangbo Tang, Junran Chen, Cheng Jin, Mengqiao Zhou, Haiyang Xie, Shusen Zheng, Penghong Song
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Cancer Communications
Subjects:
liver cancer
metastasis
DNA methylation
SERPINE2
EGFR
c‐Cbl
Online Access:https://doi.org/10.1002/cac2.12527

Internet

https://doi.org/10.1002/cac2.12527

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