Confirmation of a low HER2 positivity rate of breast carcinomas - limitations of immunohistochemistry and in situ hybridization

<p>Abstract</p> <p>Background</p> <p>Accurate assessment of the human epidermal growth factor receptor 2 (HER2) of invasive breast cancer is essential to treatment decisions since the advent of targeted therapy with the humanized monoclonal antibody trastuzumab and the...

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Bibliographic Details
Main Author: Vogel Ulrich F
Format: Article
Language:English
Published: BMC 2010-07-01
Series:Diagnostic Pathology
Online Access:http://www.diagnosticpathology.org/content/5/1/50