BRCA1 Partially Reverses the Transforming Activity of the ras Oncogene

The BRCA1 gene is associated with hereditary breast and ovarian cancers. BRCA1 fits the model of a classic tumor suppressor gene, a hypothesis supported by recent work demonstrating that expression of BRCAi inhibits growth of breast and ovarian cancer cell lines. The present study was designed to te...

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Bibliographic Details
Main Authors: Abhay Kumar, Christine Kn.ott, Kristine Kuus-Reichel, Mohammad S. Saedi
Format: Article
Language:English
Published: Elsevier 1999-11-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558699800128