Tackling malignant melanoma epigenetically: histone lysine methylation

Tackling malignant melanoma epigenetically: histone lysine methylation

Abstract Post-translational histone modifications such as acetylation and methylation can affect gene expression. Histone acetylation is commonly associated with activation of gene expression whereas histone methylation is linked to either activation or repression of gene expression. Depending on th...

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Bibliographic Details
Main Authors: Elias Orouji, Jochen Utikal
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Clinical Epigenetics
Subjects:
Histone methylation
Melanoma
Epigenetics
Histone demethylase
Histone methyltransferase
Small molecule inhibitor
Online Access:http://link.springer.com/article/10.1186/s13148-018-0583-z

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http://link.springer.com/article/10.1186/s13148-018-0583-z

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