Preclinical-to-clinical Anti-cancer Drug Response Prediction and Biomarker Identification Using TINDL
Prediction of the response of cancer patients to different treatments and identification of biomarkers of drug response are two major goals of individualized medicine. Here, we developed a deep learning framework called TINDL, completely trained on preclinical cancer cell lines (CCLs), to predict th...
Main Authors: | David Earl Hostallero, Lixuan Wei, Liewei Wang, Junmei Cairns, Amin Emad |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
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Series: | Genomics, Proteomics & Bioinformatics |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1672022923000323 |
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