The DNA methylation landscape of the human oxytocin receptor gene (OXTR): data-driven clusters and their relation to gene expression and childhood adversity

Abstract The oxytocin receptor gene (OXTR) is of interest when investigating the effects of early adversity on DNA methylation. However, there is heterogeneity regarding the selection of the most promising CpG sites to target for analyses. The goal of this study was to determine functionally relevan...

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Bibliographic Details
Main Authors: Svenja Müller, Maurizio Sicorello, Dirk Moser, Leonard Frach, Alicia Limberg, Anja M. Gumpp, Laura Ramo-Fernandez, Franziska Köhler-Dauner, Jörg M. Fegert, Christiane Waller, Robert Kumsta, Iris-Tatjana Kolassa
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02548-6